BD Brain Map
Neural Architecture of Bipolar Disorder
Spatial Correlation
01 / Overview
Neural Architecture
This surface holds 34 cortical regions measured across 6,503 people in 27 countries — their structural differences averaged into one brain.
02 / Cortex
Cortical Signatures
Orange regions mark the greatest BD-associated differences — frontoparietal thinning and temporal lobe changes mapped by the ENIGMA consortium.
03 / Subcortex
Deep Structures
The hippocampus, pallidum, and thalamus pulse through the glass — volume changes in deep structures that regulate memory, emotion, and consciousness.
04 / Transcriptomics
Molecular Expression
3,702 tissue samples from 6 post-mortem brains map 507 genes. Search a gene above to paint its expression across the architecture.
BD Score
Expression
Samples
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ENIGMA BD Working Group · Hibar et al. 2016 AHBA · Allen Institute for Brain Science fsaverage5 · FreeSurfer · nilearn
BD Brain Map
Neural Architecture of Bipolar Disorder
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